α-萘基丙酮的一种新合成方法  

A Novel Synthetic Method for α-Naphthylacetone

作　　者：韩洁[1] 王陆瑶[1] 史真[1] 

机构地区：[1]西北大学化学系,西安710069

出　　处：《应用化学》2005年第9期1036-1038,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金资助项目(No.20172041)

摘　　要：The present paper covers a novel method for the preparation of α-naphthylacetone via the addition-hydrolysis reaction of a 2-（α-naphthylmethyl）benzimidazolium salt with Grignard reagent.The IR spectrum,MS and 1H NMR of the title compound are consistent with those reported.This method provides a convenient and inexpensive access to the title compound.The mechanism for the addition-hydrolysis reaction of benzimi-（dazolium） salt with Grignard reagent and the effects of reaction conditions on the yield are discussed.The present paper covers a novel method for the preparation of α-naphthylacetone via the additionhydrolysis reaction of a 2-（α-naphthylmethyl） benzimidazolium salt with Gfignard reagent. The IR spectrum, MS and ^1H NMR of the title compound are consistent with those reported. This method provides a convenient and inexpensive access to the title compound. The mechanism for the addition-hydrolysis reaction of benzimidazolium salt with Grignard reagent and the effects of reaction conditions on the yield are discussed.

关 键 词：二甲基-(α-萘甲基)苯并咪唑盐 GRIGNARD试剂 (α-萘基)丙酮 合成 

分 类 号：O625[理学—有机化学]