铁（Ⅲ）核苷酸配位化合物与转铁蛋白的相互作用  

The Interaction Between Ferric Nucleotide Coordination Compounds and Transferrin

作　　者：王继波[1] 赵辉[1] 孙衍增[1] 

机构地区：[1]青岛医学院化学教研室

出　　处：《应用化学》1996年第1期109-111,共3页Chinese Journal of Applied Chemistry

摘　　要：铁（Ⅲ）核苷酸配位化合物与转铁蛋白的相互作用王继波，赵辉，孙衍增（青岛医学院化学教研室青岛２６６０１２）关键词转铁蛋白，核苷酸，动力学转铁蛋白广泛存在于人体细胞及体液中［１～５］，有许多关于铁在小分子配体与转铁蛋白之间交换的研究［６，７］，但铁（Ⅲ）...We have studied the kinetics of interaction between ferric nucleotide coordination compounds and transferrin with spectrophotometry. Results showed that the exchange rate of ferric ion is Fe(Ⅲ)PYR>Fe(Ⅲ)ATP>Fe(Ⅲ)ADP>Fe(Ⅲ)AMP.The exchange reactions between Fe(Ⅲ)ATP,Fe(Ⅲ)ADP or Fe(Ⅲ)PYR and deferrization transferrin are second order reactions, but the reaction mechanism of Fe(Ⅲ) ATP and Fe(Ⅲ) PYR is different from that of Fe(Ⅲ)ADP.The exchange reaction of Fe(Ⅲ) AMP is a first order reaction.

关 键 词：转铁蛋白 核苷酸 相互作用 铁 配合物 

分 类 号：Q51[生物学—生物化学]