带铜IUD对宫颈粘液中丙二醛含量影响的研究  

Investigation of the Influences of MDA Content in the Cervical Mucus of Women Wearing Copper lUDs.

作　　者：吴嵩龄[1] (亻儿)斌 杨大[1] 杨锡兰[2] 刘红蕾[1] 张颜[1] 廖善祥[1] 

机构地区：[1]湖南省计划生育研究所,长沙410005 [2]湖南医科大学附二医院

出　　处：《中国计划生育学杂志》1996年第2期89-92,共4页Chinese Journal of Family Planning

基　　金：国家计生委资助

摘　　要：应用荧光分光光度计检测503份育龄妇女宫颈粘液中丙二醛(MDA)的含量。测得最高值为6.42nmol/ml,最低痕迹量为0.01nmol/ml。有141份未测得MDA。对47例妇女放置TCu220CIUD前及放置1、6和12个月后宫颈粘液中的MDA含量进行了动态观察,结果显示,置器后宫颈粘液中MDA的含量较置器前增高(P<0.05),置器后MDA有逐渐增高的趋势,但各组间比较无统计学意义。应用TCu22C IUD3年、5年及10年者与用避孕套3年、5年及10年者比较,前者宫颈粘液中MDA含量明显增加(P<0.05)。等级相关结果显示,宫颈粘液中MDA的含量与宫颈管pH值、阴道pH值及采宫颈粘液月经周期中所处的时期不相关。文中对以上结果的临床意义进行了讨论。The MDA content in the cervical mu-eus of 503 women in childbearing age was assessed by using fluorescence spectropho-tometry in this study. The maximal value measured in this study was 6. 42 nmol/ml while the minimal trace value 0. 01 nmol/ ml. No MDA was obtained in 141 cases. Akinetic observation on the MDA content in the cervical mucus in 47 women with TCu220c IUDs before and at 1, 6and 12 months after application of the devices respectively was carried out. The results showed that MDA content in the cervical mucus was increased higher postoperatively than before the operation (P<0. 05) , there was a tendency for MDA to increase after the operative procedure, but it revealed no statistical significance in the comparison a-mont various groups. In the comparison between the cases with TCu200C IUDs for 5 and 10 years and those using other instrumental contraceptive methods for equal years, MDA content in cervical mucus of the former was increased (P<0. 05). Results obtained from grade corelation analysis revealed that changes of MDA content in the cervical mucus did not related to the pH values of cervical tract and vagina as well as the stages of the menstrual cycle (P>0. 05).

关 键 词：避孕 TCU220CIUD 丙二醛 

分 类 号：R169.41[医药卫生—公共卫生与预防医学]