冠状动脉钙化积分和亚临床动脉硬化的关系  

The Relation between Coronary Artery Calcification Score and Sub-clinical Arteriosclerosis

作　　者：卢惠玲[1] 王汐[1] 刘白鹭[1] 陈延军[1] 伴场信之 笠井贵久男 

机构地区：[1]哈尔滨医科大学附属二院,黑龙江省哈尔滨市150086 [2]日本独协医科大学病院

出　　处：《中国全科医学》2005年第17期1454-1456,共3页Chinese General Practice

基　　金：黑龙江省科技攻关项目基金资助(GC04C30102)

摘　　要：冠状动脉钙化是冠状动脉粥样硬化存在的标志。根据钙化在冠状动脉各支血管上的分布状况,可以对冠状动脉粥样硬化病变进行定位并对病变的范围和严重程度进行评估。冠心病与非冠心病患者冠状动脉钙化积分之间有显著差异,钙化积分可以发现亚临床动脉硬化,对冠状动脉狭窄进行预测。同时,钙化积分可以对有冠心病危险因素而无症状的个体发生心血管事件的可能性进行预测,被认为是一个独立的危险因素。国人的钙化率与钙化积分与西方人相比偏低,制定一个适合国人的冠状动脉钙化积分诊断标准势在必行。Coronary artery calcification is a marker of coronary atherosclerosis. The contribution of calcification in the vessels of coronary artery can be used to know the location of atherosclerosis and evaluate the extension and severity of atherosclerosis. There is significant difference between coronary artery calcification score （CACS） of coronary heart disease （CHD） and that of no CHD. CACS provides a unique opportunity to detect and quantify coronary atherosclerosis in a sub - clinical stage. It also provides a new method to estimate the stenosis of coronary artery. The use of coronary calcification assessment to predict cardiovascular events may benefit asymptomatic subjects with traditional risk factors. CACS is regarded as an independent risk factor. The rate of calcification and CACS of Chinese are lower in compared with those of western people. It is necessary to format a proper diagnostic criterion of CACS for the diagnose of CHD in Chinese population.

关 键 词：钙化积分 危险因素 动脉硬化 

分 类 号：R543.3[医药卫生—心血管疾病] R543.5[医药卫生—内科学]