人胎儿大唾液腺内NT-3的表达及意义  

The expression and significance of NT-3 in the major salivary glands of the human fetus

作　　者：伍雪芳[1] 闻明 彭彦霄[1] 柯红林[1] 贾雪梅[1] 

机构地区：[1]安徽医科大学组织学与胚胎学教研室,形态学中心实验室,合肥230032 [2]芜湖市地区医院妇产科,芜湖241001

出　　处：《安徽医科大学学报》2005年第5期435-436,共2页Acta Universitatis Medicinalis Anhui

基　　金：安徽省教育厅自然科学基金资助课题(编号:2001kj123)

摘　　要：目的对胎儿大唾液腺内NT-3的表达、分布及生物学意义进行研究.方法采用免疫组化SABC法.结果 14～32周胎儿大唾液腺内纹状管和小叶间导管上皮细胞呈NT-3免疫阳性反应.3种大唾液腺中NT-3的免疫染色强度相似,且在胚胎发育的14～32周,免疫反应强度未见明显变化.结论胎儿大唾液腺内有NT-3表达,可能与维持胎儿唾液腺的发育和功能活动有关.Objective To study the expression, distribution and biological significance of neurotrophin-3 （ NT-3 ） in the major salivary glands of the human fetus. Methods Immunohistochemical SABC method was used. Results In the major salivary glands of the fetus from 14-week to 32-week, the epithelial cells of striated and interlobular ducts showed NT-3 immunoreactivity. The immunoreactive intensity in the three major salivary glands was similar and it had no obvious chang from 14-week to 32-week. Conclusion NT-3 is present in fetal major salivary glands, which may be involved in keeping the development and functional activities of the fetal salivary glands.

关 键 词：神经营养因子3 免疫组织化学 胎儿 

分 类 号：R322.41[医药卫生—人体解剖和组织胚胎学] R394.3[医药卫生—基础医学]