甲状腺穿刺活检临床研究  

Study on clinical significance of thyroid biopsies in thyroid disease

作　　者：蒋岚[1] 朱建华[1] 陈睦虎[2] 

机构地区：[1]四川省泸州医学院附属医院内分泌科,四川泸州646000 [2]四川省泸州医学院附属医院急诊科,四川泸州646000

出　　处：《中国现代医学杂志》2005年第18期2823-2824,2827,共3页China Journal of Modern Medicine

摘　　要：目的探讨穿刺活检在甲状腺疾病诊断中的临床意义。方法对52例难于诊断的甲状腺疾病患者给予甲状腺细针抽吸细胞学检查(FNAB)和粗针穿刺活检(CNB)。结果CNB穿刺成功率100.0%,病理诊断率100.0%,FNAB敏感性:71.4%,特异性95.2%,FNAB结果与组织病理诊断符合率82.7%,16.7%以上桥本氏甲状腺炎患者甲状腺球蛋白抗体(TgAb),甲状腺微粒体抗体(TMAb)测定结果阴性。结论甲状腺疾病诊断中,当FNAB结果不肯定,有必要联合应用CNB,CNB是一种全面诊断甲状腺疾病简便、安全可靠的方法。[ Objective ] To investigate the clinical significance of thyroid biopsies in the diagnosis of thyroid diseases. [Methods] 52 uncertain diagnosis thyroid disease patients who were treated fine needle aspiration biopsy （FNAB） and coarse needle biopsy （CNB） of thyroid, cytologic and histologic diagnosis were compared in all patients. [Results] Of 52 CNB cases, all biopsies were successfully performed with Tru-Cut bioptic needle, 52 sammples （100%） were adequate for histologic diagnosis. The sensitivity of FNAB was 71.4% and the specificity was 95.2%, the accuracy of FNAB diagnosis was 80.8% contrasted to histopathology. In more than 16.74 the circulating autoantibodies TgAb and TMAb were negative with histologically diagnosed hashimoto＇s thyroiditis. [Conclusion] Analysis of the results indicates that CNB is necessary for patients with atypical thyroid disease, when the FNAB result in uncertain, CNB is a simple, safe, reliable and overall diagnosis method in thyroid diseases.

关 键 词：甲状腺疾病 活组织检查 针吸 

分 类 号：R581[医药卫生—内分泌]