香港地区慢性疲劳综合征的初步调查与中医病机探讨  

A preliminary epidemiological study and discussion on traditional Chinese medicine pathogenesis of chronic fatigue syndrome in Hong Kong

作　　者：姚韧敏[1] 丘明义[2] 

机构地区：[1]香港大学中医药学院 [2]湖北中医学院中医系,湖北武汉430061

出　　处：《中西医结合学报》2005年第5期359-362,共4页Journal of Chinese Integrative Medicine

摘　　要：目的:调查香港地区20-50岁人群疲劳与慢性疲劳综合征(chronicfatiguesyndrome,CFS)的发病情况及其中医证型与症状,探讨CFS的病机。方法:按流行病学方法,参照英国Chalder等制订的疲劳量表、美国疾病控制中心1994.年制定的CFS诊断标准及按《中药新药临床研究指导原则》中医证候指导原则的要求制定调查表,对香港地区20-50岁的普通公民进行非随机抽样调查。研究疲劳症状、CFS及常见的中医证型与症状。结果:1013位公民中,有疲劳症状的为585人,占57.8%;符合CFS诊断标准的65人,患病率为6.4%。在中医证型中,以气虚血瘀较为多见,占35.7%。在调查的54种中医症状中,出现频率最高的前8位症状依次为腰膝酸软、神疲、乏力、疼痛、失眠、健忘、脉络瘀血及头晕眼花。舌象多见舌质淡胖、淡暗,舌苔薄白、薄腻;脉象则多见沉细。结论:CFS在香港地区20-50岁人群中的患病率为6.4%。中医证型以气虚血瘀证为主。CFS的病机主要为本虚标实,以气虚、肾虚为本,血瘀为标。Objective： Our purpose is to conduct an epidemiological study of chronic fatigue syndrome （CFS） and its syndrome types and symptoms of traditional Chinese medicine （TOM） among adults （20-50 years old） in Hong Kong, and to discuss the TOM pathogenesis. Methods： Design： Cross-sectional questionnaire survey. Measures, Demographic data, CDC （1994） CFS diagnostic criteria, Trudie Chalder fatigue scale, and China national standard for TOM syndrome types criteria. Subjects： Twenty to fifty years old adults by convenient sampling. Results： One thousand and thirteen subjects were successfully interviewed. Five hundred and eighty-five subjects （57.8%） had different levels of fatigue. Sixty-five subjects （6.4%） met CFS diagnostic criteria. In terms of TOM syndrome types, blood stasis due to qi deficiency had the highest prevalence （35.7%） among CFS. In the 54 symptoms investigated in total, the first eight symptoms in order of appearing rates were soreness of loins and weakness in knees, poor spirit, lassitude, pain, insomnia, forgetting, vessels blood stasis, vertigo and dazzle. The mostly appeared tongue figures were pale and corpulent or pale dim tongue proper, white and white greasy tongue coating, and the mostly appeared pulse figure was sunken-thin. Conclusion： The point prevalence of CFS among adults of 20 to 50 years old was found to be 6.4%. The most prevalent TOM syndrome type was blood stasis due to qi deficiency. The TOM pathogenesis of CFS was deficiency of origin, mainly deficiency of qi and kidney, with excess of superficiality.

关 键 词：慢性疲劳综合征 证候 气虚血瘀 

分 类 号：R259[医药卫生—中西医结合]