应用多聚酶链反应检测前列腺液中沙眼衣原体  

PCR detection of chlamydia trachomatis in prostatic fluid of chronic prostatitis

作　　者：邵强[1] 张月清[1] 周茉[1] 张玉海[1] 于中健 

机构地区：[1]首都医科大学附属北京友谊医院泌尿外科,北京热带医学研究所,保定市第二人民医院泌尿外科

出　　处：《中华泌尿外科杂志》1996年第5期302-304,共3页Chinese Journal of Urology

摘　　要：从１９９４年１０月至１９９５年５月对７５例慢性前列腺炎患者应用多聚酶链反应（ＰＣＲ）技术检测其前列腺液中沙眼衣原体，并同时进行对照组的前列腺液检测。结果在前列腺液中沙眼衣原体阳性率为２６．７％，而且均为非细菌性前列腺炎。对照组均为阴性。前列腺按摩前初始尿和尿道脱落上皮细胞ＰＣＲ检测沙眼衣原体结果是前列腺液阳性者，尿及尿道上皮细胞均为阴性。本实验结果不仅表明沙眼衣原体是慢性非细菌性前列腺炎的病原体之一，而且为沙眼衣原体性前列腺炎提供了特异性诊断方法和治疗后监测手段。PCR detection of chlamydia trachomatis in prostatic fluid of 75 patients with chronic prostatitis was carried out and in 20 normal subjects as control.The positive rate in chronic prostatitis patients was 26.7% with it was negative in all the contros.The chlamydia trachomatis positive cases have been demonstrated to be all nonbacterial prostatitis.In 5 of the PCR positive cases,their urine and urethral scrapping cells were free from chlamydia trachomatis.The result demonstrated that chlamydia trachomatis has been one of the pathogens of nonbacterial prostatitis and PCR detection has been useful for its diagnosis and the monitoring of the therapeutic effect.

关 键 词：前列腺炎 沙眼衣原体 聚合酶链反应 

分 类 号：R697.330.4[医药卫生—泌尿科学] R374.1[医药卫生—外科学]