Chiral Recognition of Carboxylic Acids by Chiral Nitrogen Containing Calix[4]arene  

作　　者：郑炎松 肖勤 

机构地区：[1]Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074, China

出　　处：《Chinese Journal of Chemistry》2005年第10期1289-1291,共3页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 20072007）.

摘　　要：Chiral nitrogen-containing calix[4]arene was easily synthesized by the reaction of 25,27-di（2-bromoethoxy）- 26,28-dihydroxy-5,11,17,23-tetrakis（t-butyl）calix[4]arene with S-（-）-1-phenylethylamine in excellent yield, and showed good ability to recognize the enantiomers of mandelic acid and 2,3-dibenzoyltartaric acid. This finding has potential application to assay and separation of enantiomers of the carboxylic acids.Chiral nitrogen-containing calix[4]arene was easily synthesized by the reaction of 25,27-di（2-bromoethoxy）- 26,28-dihydroxy-5,11,17,23-tetrakis（t-butyl）calix[4]arene with S-（-）-1-phenylethylamine in excellent yield, and showed good ability to recognize the enantiomers of mandelic acid and 2,3-dibenzoyltartaric acid. This finding has potential application to assay and separation of enantiomers of the carboxylic acids.

关 键 词：chiral nitrogen-containing arene chiral recognition carboxylic acid. 

分 类 号：O632.6[理学—高分子化学]