The First Total Synthesis of Phebaclavin A and C  

作　　者：张宇 刘冬 李洋 曹小平 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China

出　　处：《Chinese Journal of Chemistry》2005年第10期1453-1456,共4页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 20472025） and QT Program （No. 20021001）.

摘　　要：Phebaclavin A （1） and C （2） were synthesized in 60% and 58% total yields over 5 steps from commercially available starting meterials respectively. The synthesis feature was usage of the Wittig reaction twice and solvent-free cyclizing reaction as the key steps.Phebaclavin A （1） and C （2） were synthesized in 60% and 58% total yields over 5 steps from commercially available starting meterials respectively. The synthesis feature was usage of the Wittig reaction twice and solvent-free cyclizing reaction as the key steps.

关 键 词：phebaclavin A phebaclavin C solvent-free cyclizing reaction Wittig reaction 

分 类 号：O629[理学—有机化学]