21毫米人造心脏瓣膜泵的设计及研制  

Development of 21mm aortic valvo-pump

作　　者：钱坤喜[1] 王颢[1] 王芳群[1] 茹伟民[1] 曾培[1] 袁海宇[1] 封志刚[1] 

机构地区：[1]江苏大学生物医学工程研究所,镇江212013

出　　处：《上海生物医学工程》2005年第3期160-162,167,共4页Shanghai Journal of Biomedical Engineering

摘　　要：为了研究能够长期置入主动脉瓣环的左心室辅助装置,研制出直径21毫米重27克可植入的主动脉瓣膜泵。装置包括一个转子和一个定子。转子由驱动磁钢和叶轮组成;定子装有带铁心的电机线圈和出口导叶。装置被置於主动脉瓣位置,所以不占用额外的解剖空间。血泵能像自然心脏一样直接将血液由心室输送到主动脉,不需要连接管道和旁路,因此对自然生理循环的干扰可以减到最低。血泵流量由最大到零周期变化。血液动力学测试表明,当血泵转速为17500转/分钟时,可以产生流量5升/分钟、压力增益50毫米汞柱的血流;同一转速下,当流量为零时,血泵能保持主动脉舒张压为80毫米汞柱。To investigate the feasibility of a long - term left ventricular assist device （LVAD） placed in the aortic valve annulus, an implantable aortic valve pump （21mm outer diameter, weighing 27g） was developed. The device consists a central rotor and a stator. The rotor assembly incorporates driven magnets and an impeller. The stator assembly has a motor coil with an iron core and outflow guide vanes. The device is to be implanted identical to an aortic valve replacement, occupying no additional anatomic space. The pump delivers the blood directly from left ventricle to the aortic root like natural ventricle, therefore having less physiologic disturbances to natural circulation. Neither connecting conduits nor “bypass” circuits are necessary. The pump is designed to cycle between a peak flow and zero net flow to approximate systole and diastole. Bench testing indicates that the pump could produce a blood flow of 51/min with 50mmHg pressure increase at 17,500rpm. At zero net flow rate, the pump can maintain a diastole aortic pressure against 80mmHg at the same rotating speed.

关 键 词：主动脉瓣膜泵 无接管左心室辅助装置 无旁路循环辅助 血液动力学特性 人造心脏瓣膜 毫米 左心室辅助装置 研制 主动脉瓣膜 血泵流量 设计 主动脉舒张压 力学测试 

分 类 号：R318.1[医药卫生—生物医学工程]