芳香醇类化合物高效液相色谱法的分离研究  

Study on the separation of arylalcohols and structurally-related compounds by high performance liquid chromatography

作　　者：张裕平[1] 龚文君[1] 娄天军[1] 袁倬斌[1] 

机构地区：[1]河南科技学院应用化学所

出　　处：《化学试剂》2005年第9期513-515,544,共4页Chemical Reagents

基　　金：国家自然科学基金资助项目(29875027)。

摘　　要：采用高效液相色谱法对15种芳香醇及结构相近化合物进行了分离研究。在优化的色谱条件下,8种对映体和4种非手性芳香醇同系物得到了基线分离。与单纯的紫外检测器相比,旋光检测器可方便地得到手性对映体的左旋或右旋特性。有关分离机理得到了合理的解释。A set of structurally close chiral arylalcohols and achiral arylalcohols were studied using chiralcel OD-H column as stationary phase. A HPLC system including a UV detector and an optical rotation detector was used. The optical rotation detector was a perfect supplemental tool for chiral chromatography, whichcould provide the right information about dextrorotatory and levorotatory enantiomers. The relative mechanism for enantioseparation has been elucidated according to the difference of their molecular structures.

关 键 词：高效液相色谱 对映体 芳香醇 手性 

分 类 号：O657.7[理学—分析化学]