芬太尼、舒芬太尼麻醉在心瓣膜置换术中应用疗效比较  

Comparison of the Anesthetic Effects of Sufentanil and Fentanil during Valve Replacement

作　　者：许立新[1] 佘守章[1] 周弘峰[1] 肖辉[1] 索琨[1] 

机构地区：[1]广州市第一人民医院麻醉科,广东广州510180

出　　处：《中国误诊学杂志》2005年第12期2213-2214,共2页Chinese Journal of Misdiagnostics

摘　　要：目的:评价芬太尼、舒芬太尼应用于心瓣膜置换术的麻醉效应及对术后恢复的影响。方法:50例瓣膜置换术的患者,随机分为两组,分别实施舒芬太尼(S组,n=25)和芬太尼(F组,n=25)全凭静脉麻醉。观察患者循环变化和术后恢复情况。结果:两组麻醉效果满意;诱导期间S组HR减慢发生率高于F组(P<0.05),两组MAP改变基本相似;S组术后清醒时间和气管拔拨管时间较F组为短(P<0.05),ICU停留时间两组无明显区别。结论:舒芬太尼用于心瓣膜置换术的麻醉安全有效,麻醉恢复迅速平稳。Objective：To compare the anesthetic effects of sufentanil and fentanil during valve replacement. Methods：Fifty patients undergoing valve replacement with cardiopulmonary bypass were randomly divided into two groups： sulfentanil （group S） and fentanil（group F） total intravenous anesthesia. The change of BP,HR and SpO2 was observed during anesthesia. The time of awakening from anesthesia,the extubation time and the stage of ICU were recorded. Resuits ：During induction phase, MAP was kept stable in both groups ,but the occurrence of bradycardia was significantly higher in group S （56%）than those in group F（16%）. The time of awakening from anesthesia and the extubation time was less in group S than those in group F（P〈0.05）. There were no significant difference in the average time of the stage of ICU between two groups. Conclusion：Sufentanil aneasthesia was safe and effective for patient undergoing valve replacement with eardiopulmonary.

关 键 词：麻醉 静脉内 舒芬太尼 芬太尼 麻醉恢复期 心脏缺损/外科学 

分 类 号：R726.141[医药卫生—儿科]