脂血康煎剂对血浆载脂蛋白及脂蛋白颗粒直径的影响  

Zhixuekang Decoction' s Effect on Apolipoprotein and Lipoprotein Granule Diameter

作　　者：王浩[1] 李宜芳[2] 王忠爱 郭平[1] 刘书珍[1] 王忠爱 

机构地区：[1]山东中医学院,山东250014 [2]山东中医学院附属医院,山东250014 [3]济南市中医院,山东250014

出　　处：《中国医药学报》1996年第2期23-24,共2页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：山东省教育委员会资助

摘　　要：本文探讨了中药复方脂血康煎剂对46例高脂血症患者血浆脂蛋白、载脂蛋白(apo)、高密度脂蛋白(HDL)亚组分的水平及颗粒直径的影响。发现给药8周后患者血浆甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)及apo B的水平较用药前显著降低,而HDL及其主要亚组分HDL_2和apo A-I的含量显著升高,HDL_2组分中直径较小的HDL_2a比例增加。说明脂血康煎剂能够有效地纠正高脂血症患者脂质代谢紊乱,改善血浆脂蛋白的化学组成和物理性状,预防动脉粥样硬化的发生和发展。This article studied Zhixuekang Decoction' s effect on plasma lipoprotein, apolipoprotein (apo) , high-density lipoprotein (HDL), and the contents and granule diameter of HDL' s subcon-stitution of 46 cases of hyperlipemia. The authors founded that: after eight weeks treatment the contents of triglyceride (TG),total cholesterol (TO,density lipoprotein cholesterol (LDLC) and apo B decreased more obviously, but the centent of HDL and its main substitution (HDL2 and apo A-I) increased obviously, and the proportion of mailer diameter HDL2, in HDL2 increased. The results showed that Zhixuekang decoction might control lipid metabolism disturbance of hyperlipemia , and improve the chemical composition and physical property of plasma lipoprotein and prevent the coourence and eterroration.

关 键 词：高血脂病 中医药疗法 脂血康煎剂 载脂蛋白 

分 类 号：R259.892[医药卫生—中西医结合]