肝炎后肝硬化150例血清学分析  

Serological analysis of 150 patients with hepatic cirrhosis

作　　者：杨晶[1] 杨彦麟[1] 王华信[1] 陈青峰 肖萍[1] 

机构地区：[1]兰州医学院传染病研究室

出　　处：《宁夏医学杂志》1996年第3期145-146,共2页Ningxia Medical Journal

摘　　要：本文对１５０例肝炎后肝硬化（ＣＩＲ）患者的血清标本回顾性地检测了ＨＢＶ、ＨＣＶ及ＨＤＶ感染标志，结果ＨＢＶ感染率为１００％，ＨＣＶ感染率为３９．３％，ＨＤＶ感染率为４２．０％，有６２．７％ＣＩＲ患者重重叠感染了二种以上肝炎病毒。其中二重感染率：ＨＢＶ／ＨＣＶ２０．７％，ＨＢＶ／ＨＤＶ２３．３％，三重感染率为１８．７％，均显著高于慢性乙型肝炎患者（Ｐ＜０．０１或Ｐ＜０．０５）。结果提示，ＨＢＶ、ＨＣＶ和ＨＤＶ感染与肝硬化的发生关系密切，肝炎病毒重叠感染可能导致肝病加重。HBV、HCV and HDV markers weredetermined in 150 patients with hepatic cirrhosis(CIR).The positive rate of HBV in these patients was 100 %,HCV 39.3%, HDV 42.0%, The total positive ratc ofsuperinfection of hepatitis virus in CIR was 62.7%,ofwich double infection of NBV/NCV is 20.7%,HBV/HDV 23.3%;Three-fold infection of HBV/HCV/HDV 18.7%,all being much higher as compared withchronic hepatitis B( P <0.01 or P <0.05).The resultsuggested that HBV、HCV and HDV infection may beclosely related to the development of CIR. The superin-fection of hepatitis virus will result in the worsening ofthe hepatopathy.

关 键 词：肝硬变 肝炎病毒 乙型肝炎 血清学 

分 类 号：R512.62[医药卫生—内科学] R575.2[医药卫生—临床医学]