TRFIA检测干血纸片TSH室内质控结果分析  

Analysis of the internal quality control results of testing TSH in dried blood spots by TRFIA

作　　者：刘波[1] 秦良谊[1] 马妍丽[1] 张欢欢[1] 赵文彬[1] 

机构地区：[1]江苏省连云港市第一人民医院新筛实验室,222002

出　　处：《中国妇幼保健》2005年第20期2684-2686,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨TRFIA法检测干血纸片TSH的质量控制.方法:对1年的质控干血纸片的TSH值进行统计学x、P50、s、CV、最大值、最小值等指标分析;同时对血斑不同部位的TSH值测定.结果:质控干血纸片TSH测定值的x、P50均在标准值(真值)的±20范围以内,C1、C2的CV值分别在6.6%～11.7%、3.6%～15.5%;血斑取血部位以中心到边缘的1/2处所测TSH值接近真值.结论:TRFIA法筛查新生儿先天性甲状腺功能低下症(CH)干血纸片TSH值精密度高,能有效进行质量监控.Objective： To explore the quality control of using TRFIA to test TSH in dried blood spots. Methods： Performing the statistical indicators （x, P50, SD, CV, max, min, etc） analysis to TSH in dried blood spots of quality control in a year; testing TSH in the different parts of blood spots simultaneously. Results： The testing indicators （x, P50） of TSH in dried spots of quality control both were in the ＋ 20 range of the standard value （ true value）, the CV of C1, C2 were separately in 6. 6% - 11.7%, 3. 6 - 15.5% ; the TSH testing value was in the 1/2 point of blood spots from center to side approached to the true value. Conclusions： The precision of the TSH testing value in dried blood spots tested by TRFIA to screen newborn Congenital Hypothroidism （CH） is high and the quality can be controlled effectively.

关 键 词：时间分辨荧光免疫分析法(TRFIA) 干血纸片促甲状腺素(TSH) 室内质量控制(IAC) 

分 类 号：R446[医药卫生—诊断学]