侯氏黑散对缺血性脑中风大鼠模型的保护作用  

Study on Protective Effects of HSHS on Rats with Occlusion of the Middle Cerebral Artery

作　　者：张秋霞[1] 赵晖[1] 穆阳[1] 

机构地区：[1]首都医科大学中医药学院,北京100013

出　　处：《辽宁中医杂志》2005年第10期1093-1094,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：北京市教委资助项目(KM2003100025099)

摘　　要：侯氏黑散是张仲景治疗中风的第一方。为了探求侯氏黑散治疗中风的机制,从存活率、神经功能评分、血清乳酸脱氢酶(LDH)三个方面观察其对大鼠大脑中动脉闭塞模型(MCAO)的影响。结果:侯氏黑散可以明显提高MCAO大鼠的存活率,降低MCAO大鼠的神经功能评分及其血清LDH水平。Objective： To study the protective effects of HOUSHIHEISAN（HSHS） on rats with focal cerebral ischemia injury. Methods： Focal cerebral ischemia in rats was produced by occlusion of the middle cerebral artery （MCAO）. Observe the influence of HSHS on mortality rate,neurological deficiency and determine the LDH activity during the focal cerebral ischemia. Result： HSHS has significantly protective effects against focal cerebral ischemic injury.

关 键 词：侯氏黑散 脑缺血 局灶性 LDH 动物实验 

分 类 号：R285.5[医药卫生—中药学]