热聚合法制备二苯甲酰-L-酒石酸手性分子印迹聚合物 Ⅱ.识别性能及其热力学表征  

Molecular Imprinted Polymers of Dibenzoyl-L-Tartaric Acid with Recognition Properties Prepared by Thermal Polymerization Method Ⅱ.Characterizing Molecular Recognition Properties and Their Thermodynamics

作　　者：杨座国[1] 许振良[1] 

机构地区：[1]华东理工大学化学工程研究所,上海200237

出　　处：《华东理工大学学报（自然科学版）》2005年第5期585-588,共4页Journal of East China University of Science and Technology

基　　金：国家重点基础研究发展计划(973计划)资助(2003CB615705)

摘　　要：以二苯甲酰-L-酒石酸(L-DBTA)为模板分子,甲基丙烯酸甲酯(MMA)等为功能单体,乙二醇二甲基丙烯酸酯(GDMA)为交联剂,采用热聚合方法合成了L-DBTA手性分子印迹聚合物。根据Scatchard分析表明:L-DBTA手性分子印迹聚合物中只存在一类影响聚合物识别能力的结合位点;293.15 K时结合位点的平衡离解常数为0.11 mm o l/L,最大表现结合容量为6.83 m g/g。L-DBTA的M IPs结合热力学研究表明:印迹分子L-DBTA与分子印迹聚合物手性识别基团之间的识别机理可以用Langm u ir等温吸附描述,L-DBTA的M IPs结合热力学参数如下:ΔH=8.05 kJ/m o l,ΔS=45.85 J/(m o l.K),ΔG298.15=-5.62 kJ/m o l,ΔΔH=-1.49 kJ/m o l,ΔΔS=3.55J/(m o l.K),ΔΔG298.15=-2.55 kJ/m o l;L-DBTA与M IPs相互作用速率快,表现活化能为8.05kJ/m o l。Using a functional monomer （methyl methacrylate, acrylamide, ethyl acrylate or acrylic acid） and a crosslinker （glycol dimethyacrylate）, molecularly imprinted polymers （MIPs） with recognition properties to dibenzoyl-L-tartaric acid （L-DBTA） were prepared by thermal polymerization method in the presence of a template （L-DBTA） in acetonitrile solution. Based on Scatchard analysis, one kind of binding sites was formed in the L-DBTA MIPs. At 293.15 K, its equilibrium constant （Kd） is 0.11 mmol/L while the maximum apparent binding capacity （Qm） iS 6.83 mg/g. On the basis of isothermal binding thermodynamic investigation, the recognition mechanism between L-DBTA and MIP recognition group was described by Langmuir isothermal binding. Therefore, some thermodynamic parameters are obtained： △H=8.05 kJ/mol,AS=45.85 J/（mol·K）,△G298.15=-5.62 kJ/mol,△△H=-1.49 kJ/mol,△△S= 3. 55/J（mol· K） and △△G298.15=-2.55 kJ/mol. The kinetic analysis illustrates that the interaction between L- DBTA and MIP is very fast and the apparent activation energy is 8.05 kJ/mol.

关 键 词：分子印迹聚合物 二苯甲酰-L-酒石酸 热聚合 手性识别 热力学 

分 类 号：O631[理学—高分子化学] TQ028[理学—化学]