抗感染新药仑氨西林  

New antimiaobial agent, lenampicilin

作　　者：魏敏吉[1] 齐慧敏[1] 王进[1] 肖永红[1] 林永彬 宋爱刚 王文笙 

机构地区：[1]北京大学临床药理研究所,北京100083 [2]山东鲁抗医药股份有限公司,山东济宁272021

出　　处：《中国临床药理学杂志》2005年第5期387-389,共3页The Chinese Journal of Clinical Pharmacology

摘　　要：仑氨西林是氨苄西林的前体药物,口服后水解成氨苄西林而在体内发挥 抗菌作用,其口服吸收优于氨苄西林。本文对仑氨西林的药理、药代、临床研究 情况做一综述,为临床应用提供参考。Lenampicillin is a prodrug of ampicillin. After oral administration, lenampicillin is hydrolyzed to ampicillin which is responsible for the antimicrobial activities in vivo. Lenampicillin shows better oral absorption than ampicillin. In this article, the pharmacology, pharmacokinetics and clinical studies of lenampicillin were reviewed . It may be helpful for the doctor in prescribing lenampicillin.

关 键 词：仑氨西林 抗菌 药代动力学 

分 类 号：R515[医药卫生—内科学] R978.11[医药卫生—临床医学]