肺炎清直肠浓缩液配合西药治疗小儿合胞病毒肺炎36例临床研究  

Clinical Study of Feiyanqing Rectum Condensed Liquid in Treating 36 Cases of Children Syncytial Viral Pneumonia

作　　者：杨琳[1] 尹杉杉[2] 程淑玲[1] 孙一帆[1] 袁凯[2] 刘素文[3] 冯汉鸽[1] 刘昌玉[1] 

机构地区：[1]湖北省中医院,武汉430061 [2]湖北中医学院 [3]湖北省襄樊市中医院

出　　处：《中国中西医结合杂志》2005年第10期895-898,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察肺炎清直肠浓缩液治疗小儿合胞病毒肺炎的临床疗效并探讨其作用机理。方法将入选病例随机分为西药加肺炎清直肠浓缩液治疗组(治疗组,36例)及单纯西药治疗组(对照组,36例),观察临床疗效及其对患儿免疫功能(IgA、IgG、IgE、CD3、CD4)等指标的影响。结果治疗组36例中治愈28例(77·8%),显效4例(11·1%),有效2例(5·5%),无效2例(5·6%),总有效率94·4%;对照组36例中治愈20例(55·6%),显效7例(19·4%),有效6例(16·7%),无效3例(8·3%),总有效率91·7%。治疗组治愈率明显优于对照组(P<0·05);并能提高血IgA、IgG、CD3、CD4、CD4/CD8,降低血IgE,与对照组比较差异有显著性(P<0·05)。结论肺炎清直肠浓缩液具有治疗小儿合胞病毒肺炎的作用,且未见不良反应,其机理之一可能与调节免疫功能有关。Objective To evaluate the clinical efficacy and mechanism of Feiyangqin Rectum Condensed Liquid （FRCL） in treating children syncytial viral pneumonia, Methods Seventy-two patients were randomly divided into two groups, the 36 patients in the treated group were treated with FRCL, and the other 36 patients in the control group simply treated with Western medicine. Efficacy of treatment on clinical condition and some immune function （IgA, IgG,CD3, CD4） were observed, Results In the treated group, 28 patients were cured （77.8 % ）, treatment was markedly effective in 4 patients （ 11.1% ）, effective in 2 （5.5 % ） and ineffective in 2 （5.6%）, with the total effective rate of 94.4%. The corresponding number in the control group was 20 （55.6%）,7（19.4%）,6（16.7 %）,3（8.3%） and 91.7% , respectively. The cure rate in the treated group was obviously superior to that in the control group （ P 〈 0.05）. FRCL could improve serum IgA, IgG, CD3, CD4, and CD4/CD8, lower serum IgE, these indexes in the treated group were significantly different to those in the control group （P〈0.05）. Conclusion FRCL had the action in treating children syncytial viral pneumonia without any adverse reaction, one of its mechanisms might be related to its regulation on immune function.

关 键 词：小儿合胞病毒肺炎 肺炎清直肠浓缩液 临床研究 合胞病毒肺炎 西药治疗 浓缩液 肺炎清 直肠 小儿 CD4/CD8 

分 类 号：R725.6[医药卫生—儿科]