中药SS糖浆治疗口干燥症的临床研究  

Clinical Study of SS Syrup in Treating Xerostomia

作　　者：郑凌艳[1] 俞创奇[1] 胡北平[1] 

机构地区：[1]上海市第二医科大学附属第九人民医院口腔颌面外科,上海200011

出　　处：《中国中西医结合杂志》2005年第10期899-901,共3页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：上海市卫生局中药制剂新药开发项目基金(No.Y0203)

摘　　要：目的比较中药SS糖浆和匹鲁卡品治疗口干燥症的临床效果。方法将符合入选标准的38例患者随机分为两组,分别给予SS糖浆或匹鲁卡品。通过对口干问卷调查表、静态唾液总流量和动态唾液总流量3个指标的观察,记录用药前,用药后1、2和4周的数值,进行统计学分析。结果SS糖浆组3个指标均显示了用药前和用药后1周、2周、4周比较,差异有显著性(P<0·05)。匹鲁卡品组用药前与用药后1周、2周、4周(除动态唾液总流量第1周外)比较,差异均有显著性(P<0·05)。结论SS糖浆对改善口干症状有良好的疗效。Objective To compare the clinical efficacy of SS syrup, a Chinese medicine, and pilocarpine in treating patients with xerostomia. Methods Thirty-eight patients conformed to the inclusive criteria were randomly divided into two groups, they were treated by SS syrup （SS group） and pilocarpine （control group） respectively. Three indexes, i.e. questionnaire of dryness in mouth, total static salivary flow and dynamic salivary flow, before treatment, 1, 2 and 4 weeks after treatment were recorded and statistically analyzed. Resuits Significant difference was shown in the 3 indexes in the SS group between before treatment and 1, 2 and 4 weeks after treatment （P 〈 0.05）, while in the control group significant difference was shown between before treatment and 1,2, and 4 weeks after treatment except for total dynamic salivary flow after 1 weck treatment （P 〈0.05）, Conclusion SS syrup, which has no adverse reaction, no contraindication, could be taken chronically, and shows good efficacy in improving the symptoms of xerostomia.

关 键 词：口干燥症 中药SS糖浆 匹鲁卡品 SS糖浆 临床研究 治疗 中药 问卷调查表 统计学分析 用药前 

分 类 号：R276.8[医药卫生—中医五官科学]