纳米化技术对抗疲劳药物的增效研究  

Study of anti-fatigue improvement on nanometer-particulate medicine

作　　者：谷峰[1] 姜辉[1] 汪德清[1] 宋淑珍[1] 董矜[1] 田亚平[1] 

机构地区：[1]解放军总医院生化科

出　　处：《军医进修学院学报》2005年第5期348-349,共2页Academic Journal of Pla Postgraduate Medical School

基　　金：解放军总医院成果转化基金(03YC09)

摘　　要：目的:探讨药物力谷源不同制作加工工艺后的抗疲劳功能差异。方法:普通力谷源和力谷源纳米制剂分别喂养小鼠,通过小鼠负重游泳实验观察不同喂养组之间游泳时间差异,分析抗疲劳能力。结果:与对照组及力谷源喂养组比较,力谷源纳米制剂喂养组可明显延长小鼠负重游泳时间(P<0.001)。结论:力谷源纳米制剂具有抗疲劳作用。Objective ：To observe the effect of nanometer-particulate LiGuYuan capsule and common LiGuYuan capsule on anti-fatigue in mice. Methods：Mice are treated with nanometer-particulate LiGuYuan capsule and common LiGuYuan capsule. Anti- fatigue of mice was observed by the duration of exhaustive swimming. Result： It showed that compared with the control group and common LiGuYuan capsule- treatment group, time of exhaustive swimming of the mice in the nanometer- particulate LiGuYuan capsue group is more long significantly（P 〈 0.001）. Conclusion：Nanometer- particulate LiGuYuan capsule can anti-fatigue.

关 键 词：纳米化技术 抗疲劳药物 加工工艺 力谷源胶囊 中药制剂 

分 类 号：R977.9[医药卫生—药品]