血水草生物碱对钉螺生殖腺超微结构的影响  

Effect of Eomecon chionantha alkaloids on ultrastructure of genital system of Oncomelania hupensis

作　　者：孙慧[1] 黄琼瑶[1] 彭飞[1] 刘年猛[1] 徐锡萍[2] 胡琦[1] 冯芳[1] 

机构地区：[1]湖南师范大学医学院寄生虫学教研室,长沙410006 [2]中南大学湘雅医学院电镜室

出　　处：《中国血吸虫病防治杂志》2005年第5期377-378,共2页Chinese Journal of Schistosomiasis Control

基　　金：湖南省教育厅重点资助项目(No.03A058)

摘　　要：目的观察血水草生物碱对钉螺生殖腺的影响,探讨血水草生物碱杀灭钉螺的作用机理。方法用血水草生物碱浸泡钉螺48h,解剖钉螺,取雌、雄生殖腺以常规方法制作电镜切片,用日立H-600型透射电镜观察组织结构变化。结果血水草生物碱浸泡后,钉螺卵细胞明显萎缩,精原细胞固缩。结论血水草生物碱对钉螺的生殖腺造成严重损伤。Objective To explore the mechanism of Eomecon chionantha alkaloids （ECA） against Oncomelania hupensis by means of observing the effect of ECA on the genital system of O. hupensis. Methods O. hupensis was dissected after immersed in ECA for 48 hours ; the testes and ovary were took out and made for electron microscopy samples by the conventional method. The change of structure was observed by Hitach H-600 Transmission Electron Microscope. Results After immersed in ECA, oocyte of O. hupensis was obviously atrophied and spermatogonium pyknosis occured. Conclusion ECA could damage the genital system of O. hupensis seriously.

关 键 词：血水草 生物碱 钉螺 生殖腺 电镜 

分 类 号：R383.24[医药卫生—医学寄生虫学]