三生饮对小鼠缺氧及兔血流动力学、血气、pH值的影响  

The Effects of Sanshengyin Decoction on Hypoxia in Miceand Hemodynamics,Blood Gas,and pH Value in Rabbits

作　　者：孙爱续[1] 王秀荣[1] 高晓山[1] 

机构地区：[1]中国中医研究院中药研究所

出　　处：《中国实验方剂学杂志》1996年第4期18-21,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局青年基金

摘　　要：观察了三生饮对小鼠缺氧及兔血流动力学、血气、ｐＨ值的影响。结果表明：三生饮具有延长小鼠断头喘气时间，增加兔脑血流量、股动脉血流量、心率及动脉收缩压，降低动脉舒张压及颈动静脉氧分压差的作用。本项研究阐明了其疗效及作用机理，为临床用药提供了药理学依据。The effects of Sanshengyin decoction on hypoxia in mice and hemody-namics,blood gas,and pH value in rabbits were observed.The results showed that Sanshengyin decoction had actions of marked antihypoxia,significantly increasing cerebral blood flow,femoral blood flow,heart rate and artery systolic bIood pres-sure,and decreasing artery diastolic blood pressure and difference of oxygen frac-tional pressure between carotid artery and cervical vein,The findings explained the therapeutic effect and its mechanism of Sanshengyin.decoction and provided for pharmacological basis of its application in clinic.

关 键 词：三生饮 中药 方剂 血流动力学 缺氧 血气 PH值 

分 类 号：R289.5[医药卫生—方剂学]