双腔起搏器治疗肥厚性梗阻型心肌病随访观察  

A Follow-up Study of Dual-Chamber Pacing in Patients with Hypertrophic Cardiomyopathy

作　　者：张兴凯[1] 张文广[1] 马小明[1] 许金东[1] 

机构地区：[1]解放军第五医院心脏呼吸内科,银川750004

出　　处：《宁夏医学院学报》2005年第5期379-380,共2页Journal of Ningxia Medical College

摘　　要：目的观察双腔起搏器(DDD)对肥厚性梗阻型心肌病(HOCM)患者的远期临床效果及心脏结构形态的变化。方法对8例HOCM患者术前与术后临床症状及多普勒超声心动图(UCG)检查结果进行对比分析,比较患者临床症状及心脏形态变化。结果双腔起搏3年后,2例临床症状消失,5例临床症状明显减轻或改善,1例改善不明显,但未加重。3例发生过晕厥患者未再出现晕厥,心功能明显改善,随访中所有病例存活。8例患者超声心动图均显著改变,尤其二尖瓣收缩期前向运动(SAM)、左心室流出道(LVOT)宽度、左室流出道血流速度(LVP)改善更为显著,左室后壁厚度(LVPW)有缩小的趋势,左室射血分数(LVEF)也明显改善,肥厚的心室间隔显著变薄(P<0.05)。结论双腔起搏器治疗HOCM远期效果明显。Objective To analyze the long- term effectiveness of dual - chamber pacing in patients with hypertrophic cardiomyopathy （HOCM）.Methods Eight patients with HOCM treated with dual- chamber pacing for 3 years were included in this study. Clinical symptoms and UCG changes were observed and analyzed before dual- chamber pacing installed and 3 years later. Results After 3 years of Dual- chamber pacing, clinical symptoms vanished in two cases and improved in 5 cases. One had no changes, but not yet become graver. Fainting did not occur again in 3 cases and heart function improved. All patients were alive in follow- up. Some indexes of UCG improved manifestly. They were valvula mitralis SAM, the width of LVOT, the blood flow rate of LV, the thickness of LVPW. LVEF elevated obviously and Hypertrophic ventricular septum thinningz（ P 〈 0.05） .Conclusion A good long- term outcome could be obtained in patients with HOCM treated with dualchamber oacina.

关 键 词：肥厚性心肌病 多普勒超声心电图 双腔起搏器 心脏起搏 

分 类 号：R542.2[医药卫生—心血管疾病]