肾性贫血患者血清铁参数检测的临床意义  

The Clinical Meaning of Iron-status Indices in Patients with Renal Anemia

作　　者：马恩龙 石宏宴[2] 董枫[2] 任欣[3] 

机构地区：[1]大连卫生学校,辽宁省大连市116622 [2]大连医科大学 [3]大连大学医学院

出　　处：《医学理论与实践》2005年第10期1145-1146,共2页The Journal of Medical Theory and Practice

摘　　要：目的:探求肾性贫血患者血清铁参数的临床诊断价值和其改变的原因。方法:采用ACT、化学分析和ELISA测定78例慢性肾衰患者的Hb、红细胞比容和血清铁参数。结果:慢性肾衰病人血清中SI、TIBC、TS显著高于健康群体(n=50,P<0.05),病人的血清(SF)显著低下(P<0.05)。结论:肾性贫血反映铁代谢紊乱,转运发生障碍。Objective：To study diagnostic values of iron- status indices in patients with renal anemia, and the reasons of it＇s changes. Methods：Hemoglobin（Hb）, hemoglobin concentration（Hct） and the iron-status indices in 78cases of chronic renal failure （CRF） and 50 healthy subjects were tested with ACT, chemical analysis and ELISA. Results： The serum iron（SI）, total ironbinding capacity（TIBC） and transferring saturation（TS） in patients with CRF were significandy lower than those of healthy subjects （ P 〈 0.05）. On the contrary, the serum ferritin （SF） is significantly higher in patients than that in healthy subjects （ P 〈 0,05）. Conelusion： Renal anemia can reflect functional iron deficiency, its metabolism disorder and disturbance of its transportion.

关 键 词：肾性贫血 血清铁 总铁结合力 运铁蛋白饱和度 血清铁蛋白 

分 类 号：R446.11[医药卫生—诊断学]