米槁心乐滴丸对动物药效学的研究  

Pharmacodynamic study of Migaoxinle Dripping Pills on mice

作　　者：付原 [1] 严德凤 [1] 李开斌 [2] 隋艳华 [2] 

机构地区：[1]贵阳医学院,附属医院,中心实验室,贵州,贵阳,550004 [2]贵阳中医学院,贵州,贵阳,550002

出　　处：《大连医科大学学报》2005年第5期351-352,共2页Journal of Dalian Medical University

摘　　要：[目的]观察米槁心乐滴丸对实验动物耐缺氧及血液流变学的影响。[方法]利用肾上腺素复制大鼠急性“血瘀”证模型和应用常压耐缺氧实验方法,观察米槁心乐滴丸口服给药对大鼠模型防治作用。[结果]米槁心乐滴丸能提高小鼠耐缺氧能力,对大鼠“血瘀”证有防治作用。[结论]米槁心乐滴丸可明显降低心肌耗氧量和改善血液流变性。[ Objective] To investigate the effects of Migaoxinle Dripping Pills （Migao Cinnamon and Bulbus AUii Macrostemi） （MDP） on mice with resistance to hypoxemia and hemorrheology. [ Methods] The blood stasis syndrome models of mice was built using adrenalin（Adr） and the normal resistance to hypoxemia was used, MDP was given through po. to observe its effects of protection and treatment. [ Results] MDP could increase the ability of resistance to hypoxemia and have protective and treatment effects of mice with blood stasis syndrome. [ Conclusion] MDP could significantly decrease the oxygen consumption of cardiac muscle and improve the hemorrheological parameters.

关 键 词：米槁心乐滴丸 血瘀证 血液流变学 

分 类 号：R285[医药卫生—中药学]