幽门螺杆菌对成人缺铁性贫血治疗影响的临床研究  

Clinical study on Helicobacter pylori influence therapeutics of iron deficiency anemia in adults

作　　者：陈伦华[1] 罗和生[2] 

机构地区：[1]武汉大学人民医院血液科,湖北武汉430060 [2]武汉大学人民医院消化科,湖北武汉430060

出　　处：《中国现代医学杂志》2005年第19期2969-2971,共3页China Journal of Modern Medicine

摘　　要：目的研究幽门螺杆菌(HP)对HP阳性的缺铁性贫血治疗的影响。方法以62例HP阳性的慢性胃炎引起的缺铁性贫血(IDA)为对象。随机分为两组,A组(31例)给予抗HP加铁剂治疗,B组(31例)给予单纯铁剂治疗,动态观察两组的血液学和铁代谢指标变化。结果A组外周血的血红蛋白(HGB)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)以及血清铁(SI)和血清铁蛋白(SF)恢复明显比B组快,尤其以储存铁SF在治疗后期(60d)的恢复更为明显(P<0.01)。结论在治疗HP阳性的慢性胃炎引起的IDA过程中,抗HP治疗能明显提高铁剂的治疗效果。[Objective] To study Hdicobacter pylori （HP） influence the therapeutics of iron deficiency Anemia （I- DA） in adult. [Method] 62 IDA patients caused by chronic gastritis with HP positive were didived into two groups at random, A group （31 cases） were treated with ferrous succinate and anti-HP, B group （31 cases） were treated with ferrous succinate, the markers of hematology and iron metabolism were dynamic observed. [Result] The recovery of hemoglobin （HGB）, mean corpuscular volume （MCV）, mean corpuscular hemoglobin （MCH） in peripheral blood and serum iron （SI）, serum ferritin （SF） are more quickly in A group than that of in B group. Especially, the SF level of A group was significant higher than that of B group at sixtieth day （P 〈0.01）. [Conclusion] It can increase the therapeutic effect of ferrous succinate when anti-HP was given in the IDA patients caused by chronic gastritis with HP positive.

关 键 词：幽门螺杆菌 缺铁性贫血 治疗 

分 类 号：R378.2[医药卫生—病原生物学]