独活寄生汤加减对男性强直性脊柱炎患者骨密度的影响  

Effects of “Duhuo Jisheng Decoction” on Bone Mineral Density in Men with Ankylosing Spondylitis

作　　者：许敬人[1] 邓惠民[1] 孙勤[1] 庄键 

机构地区：[1]上海市东方医院,上海200120 [2]上海港医院,上海200120

出　　处：《上海中医药杂志》2005年第11期33-34,共2页Shanghai Journal of Traditional Chinese Medicine

摘　　要：为评价独活寄生汤对男性强直性脊柱炎(AS)患者骨密度的影响,将65例男性AS患者随机分为治疗组(35例,用独活寄生汤加减治疗)和对照组(30例,用柳氮磺吡啶治疗),疗程6个月.采用双能X线骨密度仪测量2组治疗前后腰椎2～4及股骨颈的骨密度,并同时测量2组治疗前后脊柱活动度相关指标.结果:治疗组治疗后腰椎和股骨颈的骨密度显著增加(P＜0.05,P＜0.01),对照组无显著性差异;2组治疗后脊柱活动度相关指标方面均有改善,且治疗组优于对照组(P＜0.05).提示独活寄生汤能提高男性强直性脊柱炎患者的骨密度,改善脊柱的活动.To observe the effects of “Duhuo Jisheng Decocton” on the bone mineral density （BMD） in men with ankylosing spondylitis （AS）, 65 subjects were divided randomly into two groups： treatment group in which 35 cases were treated with “Duhuo Jisheng Decoction”and control group in which 30 cases were treated with SASP. BMD of second to fourth lumbar vertebrae and femoral neck were measured by dual energy X-ray absorptiometry （DEXA） before and after treatment. The items concerning spine movement were also measured in the meantime. Results： The BMD of lumbar vertebrae and femoral neck was raised in treatment group （ P〈0.05 ）. The BMD improved little in control group; the items concerning spine movement were improved in both groups, with better effects in treatment group than in control group（P〈0.05）. It is showed that “Duhuo Jisheng Decoction” can significantly improve BMD in AS men, which may be helpful for spine movement.

关 键 词：强直性脊柱炎 独活寄生汤 骨密度 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]