电喷雾质谱法和高效液相色谱法对dpq、ttd合成机理探讨  

Mechanism for Preparation of Condensed Rings Compounds Containing Nitrogen Analyzed with HPLC and ESI-MS

作　　者：陶建清[1] 孙冲[1] 张利民[2] 费正皓[1] 顾志国[3] 

机构地区：[1]盐城师范学院化学系,盐城224002 [2]江苏省环境科学研究院重点实验室 [3]南京大学配位化学国家重点实验室

出　　处：《应用化学》2005年第11期1234-1238,共5页Chinese Journal of Applied Chemistry

基　　金：江苏省教育厅自然科学基金项目(No.02KJB150010);江苏省环境科学研究院重点实验室开放基金项目(No.KF0407)

摘　　要：应用电喷雾质谱(ESI-MS)和高效液相色谱(HPLC)等谱学手段研究phen-5,6-d ione与乙二胺、二胺基顺式丁烯二腈等物质的相互作用。研究发现,羰基和胺基将首先加成形成中间体,然后脱水形成双键。如果能形成共轭体系,将进一步脱氢形成稳定的稠环共轭化合物。The interactions between phen-5,6-dione and ethyldiamine or cis-diaminomaleonitrile were studied via high performance liquid chromatography and electrospray ionization mass spectrometry respectively. The results show that the intermediate from the addition reaction between the carbonyl and amine groups formed first, it was further dehydrated to form the double bond. And if a conjugated system could be formed, the resulting intermediate would be dehydrogenated further into conjugated compounds of condensed nings.

关 键 词：电喷雾质谱 高效液相色谱 反应机理 配体dpq 配体ttd 

分 类 号：O657.6[理学—分析化学] O657.7[理学—化学]