Visualine—II法和气－质联用法检测尿液中吗啡的对比研究  

A COMPARATIVE STUDY OF MORPHINE TESTING IN URINEBY VISUALINE -II AND GC/MS METHODS

作　　者：徐伟仁 陆敏珏[1] 鞠小弟 吕华沙[1] 姚文豪[1] 毛莉君[1] 

机构地区：[1]上海市公安局安康医院

出　　处：《中国药物依赖性通报》1996年第2期82-85,共4页

摘　　要：用Ｖｉｓｕａｌｉｎｅ—ＩＩ快速毒品检测盒（Ｖ—ＩＩ）和气－质联用法（ＧＣ／ＭＳ）对３０例海洛因依赖者进行尿液中吗啡的系统检测。在２０３份尿样中，对比ＧＣ／ＭＳ的结果，Ｖ－ＩＩ阳性率为９５．７％，假阴性率为４３％，假阳性率为３．７％；当尿样中吗啡含量＞１．０ｕｇ·ｍｌ－１时，Ｖ－ＩＩ阳性率为１００％。而对照４０例正常人的尿样检测结果，Ｖ－ＩＩ均呈阴性反应。研究结果表明，Ｖ—ＩＩ的灵敏度和准确性均较高，且具有简便、快捷的特点，是一种比较理想的快速检测工具。Morphine in 203 urine samples was measured qualitatively by bothVisualine -II test and gas chromatography - mass spectrometry(GC/MS) in 30 cases ofheroin addicts. In comparison with the results of GC/ MS, the Visualine -II's positive rate was 95. 7%, the false negative rate was 4.3% and its false positive rate was3. 7%. Mean while, the positive reaction was revealed in all urine samples when the concentration of morphine was >1.0μg. ml-1. Whereas negative results were observed inall the 40 normal control subjects. Our results showed that Visualine-II was simple andrapid and of higher sensitivity and accuracy. Thus it was a good screening method forclinical practice.

关 键 词：海洛因依赖 吗啡 气-质联用法 Visualine-II法 

分 类 号：R595.504[医药卫生—内科学] R446.12[医药卫生—临床医学]