扶正抑癌冲剂配合化疗治疗微小残留白血病的临床与实验研究  

Clinical and Experimental Studies on Micro - Residual Leukemia Treatedwith Fuzheng Yiai (Resistance -supporting Tumor- inhibiting) Infusion Coordinated with Radiotherapy,

作　　者：王乙忠 周霭祥[1] 王志平 展昭明 马军 郭晓峰 

机构地区：[1]中国中医研究院西苑医院 [2]山西化工厂医院 [3]哈尔滨市血液病研究所 [4]大同市中医院

出　　处：《中医杂志》1996年第9期535-538,共4页Journal of Traditional Chinese Medicine

摘　　要：扶正抑癌冲剂是治疗微小残留白血病(MRL)的有效药物,治疗后患者全身状况及并发症有明显的改善,该方显著提高MRL患者的免疫功能,提高完全缓解率及生存质量,延长患者生存期。对DNA指数、DNA非整倍体率、Ph’染色体、BCR/ABL基因等各项指标研究表明,该方具有抑制或消除恶性克隆的作用。体外细胞培养证实,本方具有刺激正常骨髓细胞增殖作用,但对白血病细胞无刺激作用。动物实验表明,该方可明显延长MRL动物模型的生存期。Fuzheng Yiai Infusion is an effective remedy for micro - residual leukemia (MRL). It yields marked mitigation on the geneval condition of the patient and prevents complications by substantially improves the patients immunity, elevates the rate of total remission and living quality, prolongs the survival period. Studies on the indices including DNA index, rate of DNA non - uneuploid, ph' chromosome, and BCR/ ABL gene, showed that the recipe can inhibit or eliminate the actions of malignant clone. In vitro cultivation of cells proved that the recipe yields stimulating action on the proliferation of normal marrow cells, yet yields no stimulating action on leukemic cells. Animal experiments reveal this recipe markedly prolongs the survival period of MRL animal models.

关 键 词：白血病 中医药疗法 扶正抑癌冲剂 

分 类 号：R273.370.5[医药卫生—中西医结合]