HIV/HCV混合感染CD4^+细胞计数与HCV病毒载量的相关性研究  

Correlation between CD4^+ count and plasma HCV viral load in HIV/HCV co- infections

作　　者：秦红波[1] 蔡卫平[1] 陈谐捷[1] 陈劲峰[1] 

机构地区：[1]广州市第八人民医院感染科,510060

出　　处：《实用医学杂志》2005年第19期2133-2134,共2页The Journal of Practical Medicine

基　　金：广东省医学科学技术研究基金资助项目(项目编号:A2001583)

摘　　要：目的:通过分析HIV/HCV混合感染的CD4+细胞计数与HCV病毒载量(HCVVL)的相关性,探讨HIV感染时细胞免疫状况对HCV病毒水平的影响。方法:同时测定CD4+细胞计数与HCV-RNA定量,研究两者的相关性。结果:CD4+细胞计数与HCV-RNA定量不相关(r=-0.120,P=0.479)。结论:HIV/HCV混合感染时,细胞免疫状态对HCV病毒载量没有明显影响。Objective To analyze the correlation between CD4^＋ count and HCV viral load in HIV/HCV co-infections, in order to investigate the influence of the cellular immunity on the HCV viral load in HIV infections. Methods To detect the CD4^＋ count and HCV-RNA level in 37 patients with HIV/HCV co-infections at the same time, and then study the association of them from Aug, 1999 to Sep, 2004. Results There was no correlation between CD4^＋ count and HCV-RNA level（ r = -0. 120, P=0.479）. Conclusion When HIV/HCV co-infected, the cellular immunity had no influence on the HCV viral load.

关 键 词：HIV 肝炎病毒 重叠感染 病毒载量 CD4淋巴细胞计数 CD4^+细胞计数 HCV混合感染 HIV感染 RNA定量 细胞免疫状况 

分 类 号：R512.91[医药卫生—内科学] R512.63[医药卫生—临床医学]