锌转运蛋白基因研究进展  

Research Advances about the Genes of Zinc-transporting Proteins

作　　者：武泰存[1] 房蓓[2] 王景安[1] 

机构地区：[1]天津师范大学化学与生命科学学院,天津300074 [2]天津医科大学,天津300070

出　　处：《西北植物学报》2005年第10期2139-2144,共6页Acta Botanica Boreali-Occidentalia Sinica

基　　金：天津市应用基础研究重点项目资助(033803711)

摘　　要：锌作为一种重要的微量元素参与了植物体内广泛的生理和生化过程,本文详细介绍了涉及Zn2+吸收转运的Z IP基因家族(ZRT/IRT相关蛋白)和CDF(C ation d iffus ion fac ilitator)家族。Z IP家族转运蛋白主要负责将Zn2+等二价阳离子跨膜转运进细胞内,以完成细胞内多种生理生化反应。CDF家族转运蛋白主要负责将过量的Zn2+运出细胞,或者将细胞内过量Zn2+进行区室化隔离,降低Zn2+对细胞的危害作用。Z IP家族转运蛋白和CDF家族转运蛋白的相互协调使得Zn2+在细胞和有机体水平上维持着稳态,进而为细胞内各种生理生化反应的进行提供一种保障机制。Zinc participates in a wide range of physiological and biochemical processes as an important trace element and thus the paper introduces the ZIP （ZRT/IRT-like proteins） and CDF families of zinc transporters in details. ZIP family （ZRT/IRT-like proteins） of zinc transporters is responsible for transporting Zn^2＋into cells through cell membrane for completing many physiological and biochemical reactions. CDF family of zinc transporters is mainly responsible for transporting surplus zinc out of cells or secluding it through cellular compartmentalization to reduce Zn^2＋ cellular damage. ZIP and CDF families of zinc transporters collaborate to maintain a balanced Zn^2＋ state on cellular and body levels and thus forming a safeguard system for various physiological and biochemical reactions in cells

关 键 词：ZN^2+ ZIP CDF 转运蛋白 

分 类 号：Q789[生物学—分子生物学]