苓桂术甘汤对肉鸡腹水综合征的防治作用  

The Preventive Effect of LGZG Tang on Ascites Syndrome of Broiler

作　　者：王文魁[1] 齐永华[2] 程佳[1] 李雪莲[1] 周利青[1] 郭娜[1] 张映[1] 刘晋平[1] 宋金香[3] 白建[1] 

机构地区：[1]山西农业大学动物科技学院,太谷030801 [2]河南科技学院动物科学系,新乡453003 [3]山西农业大学图书馆,太谷030801

出　　处：《畜牧兽医学报》2005年第11期1215-1222,共8页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：山西省自然科学基金(20001088)

摘　　要：将15日龄艾维茵肉鸡分成5组,一组在常温(21±1)℃下饲养,作为正常对照组(N);其余4组在低温(11±1)℃下饲养以诱发腹水综合征,其中模型对照组(C)不给任何药物,维生素组(V)饮水中添加VC(0.5 g/L)和VE(0.1 g/L),2个试验组(T1和T2)分别给予不同剂量(0.4和0.8 mL/kg bw)的苓桂术甘汤。结果显示,C组的腹水发病率、腹水心脏指数(AHI)、红细胞压积(PCV)、红细胞数、血红蛋白(Hb)及丙二醛(MDA)含量、血清α-羟丁酸脱氢酶(-αHBDH)、谷草转氨酶(GOT)和谷丙转氨酶(GPT)均显著高于N组;而3种抗氧化酶[超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)]的活性则显著降低;2个试验组及V组的上述检测指数都得到明显改善,表明苓桂术甘汤能增强肉鸡的抗氧化能力,具有防治肉鸡腹水综合征的作用。Avian broilers were randomly divided into 5 groups （54 birds respectively）at the age of 15 d, one was normal control group（N） which was reared at normal ambient temperature, （21±1）℃; the other four groups were reared at low ambient temperature, （11±1）℃, to induce ascites syndrome. These latter four groups were： control group（C） not given any medicine, vitamine group（V） given VC（0. 5 g/L） and VE（0. 1 g/L） in drinking-water, test group T1 and test group T2 given tested Chinese medicine, LGZG Tang ,0.4 mL/kg bw and 0.8 mL/kg bw separately in drinking-water. The results showed that the incidence of ascites syndrome, ascites heart index （AHI）, packed cell volume（PCV）, red blood cell count（RBC）, hemoglobin（Hb） and malondialdehyde（MDA）, α- hydroxybutyrate dehydrogenase（α-HBDH） and two tansaminases [glutamic-oxaloacetic transaminase （GOT） and glutamic-pyruvic transaminase （GPT）] in the serum were significantly higher in the C-group than in the N-group; but the three antioxidases [superoxide dismutase （SOD）, glutathione peroxidase（GSH-Px） and catalase] were significantly lower in the C-group than in the N-group. All the parameters mentioned above were improved in the test groups. It was revealed that LGZG Tang was able to improve the antioxidation capability of the broilers and prevent ascites syndrome.

关 键 词：肉鸡腹水综合征 苓桂术甘汤 自由基 抗氧化酶 丙二醛 Α-羟丁酸脱氢酶 谷草转氨酶 谷丙转氨酶 

分 类 号：S853.75[农业科学—临床兽医学]