榛花对四氧嘧啶性糖尿病小鼠胰岛β细胞再生修复的影响  

Effects of regeneration and renovation of Hazel' s flower on pancreas islet β cell in diabetic mice induced by alloxan

作　　者：蔡英兰[1] 金香子[1] 金美善[1] 李善花[1] 

机构地区：[1]延边大学基础医学院人体解剖学与组织胚胎学教研室,吉林延吉133000

出　　处：《延边大学医学学报》2005年第3期177-179,共3页Journal of Medical Science Yanbian University

摘　　要：[目的]观察榛花对糖尿病小鼠胰岛β细胞再生修复的影响.[方法]用四氧嘧啶制作小鼠糖尿病模型.设立正常对照组、糖尿病对照组、药物对照组及大、中、小剂量(5.00,2.50,1.25 mL/kg)榛花浓缩液实验组,实验周期为3周,其后用免疫组织化学方法观察胰岛β细胞.[结果]大、中、小剂量榛花浓缩液实验组小鼠胰岛β细胞数量与糖尿病对照组相比较无明显差别.[结论]榛花对受损胰岛β细胞的再生修复影响不大.OBJECTIVE To observe the effects of regeneration and renovation of Hazel ＇ s flower on pancreas islet β cell in diabetic mice. METHODS The diabetic models of mice were induced by alloxan. The mice were divided into normal control group, model control group, medicine control group, and high, middle and low dosages Hazel＇ s flower groups, The mice in high, middle and low dosages Hazel ＇ s flower groups were given 5.00,2.50,1.25 mL/kg dosages of Hazel＇ s flower individually, After 3 weeks of the experimental period, the pancreas islet β cell was observed by immunohistochemical method, RESULTS the The amouts of pancreas islet t3 cell of high, middle and low dosages Hazel＇ s flower groups had no significant difference from model control group. CONCLUSION Hazel ＇ s flower hadn＇ t the effects on restoring and repairing the damged pancreas islet β cell.

关 键 词：糖尿病 实验性 胰岛 植物 药用 小鼠 

分 类 号：R285.5[医药卫生—中药学]