冠状动脉造影剂临床应用研究  

A Clinical Study of Constrast Mediums

作　　者：李洪稳[1] 张军[1] 周继新[1] 尚爱英[1] 王海英[1] 王玉刚[1] 王钢[1] 元柏民[1] 

机构地区：[1]河北省沧州市中心医院心脏内科,沧州061001

出　　处：《中国医药导刊》2005年第5期350-351,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨应用非离子型造影剂行冠状动脉造影术前用相应剂型作碘过敏试验预测临床过敏反应的可行性.方法:回顾性分析5800例接受冠状动脉造影患者,30%复方泛影葡胺碘过敏试验阴性5516例,阳性284例.对284例患者再行非离子造影剂碘普胺(优维显)/三碘三酰普胺六醇苯(欧乃派克)试验为阴性,并行冠状动脉造影.结果:284例30%复方泛影葡胺碘过敏试验阳性,而非离子型碘普胺/三碘三酰普胺六醇苯试验阴性,应用相应剂型行冠状动脉造影临床未发生过敏反应.结论:应用非离子型造影剂行冠状动脉造影,术前用相应剂型造影剂作碘过敏试验预测临床过敏反应具有高敏感性和特异性,无假阳性发生.Objective： To investigate the feasibility forecasting the clinical allergic reaction of the radiography non - ionic constrast mediums before Coronary angiography. Methods： The review analysises 5800 examples who underwent the coronary angiography, 30% compound meglumine diatrizoate injection idiodine allergy test negative 5 516, positive 248. Using the non - ionic radiographyIopromide （Ultravist）/Iohexolum（Omnipaque） medicinal experiments to 248 positive patients displaynegative.Results： Thecases using 30% compound meglumine diatrizoatc injection idodine allergy experiments display positive, but using the non - ionic radiography Iopromide/Iohexolum experiments display negative, the application corresponding form of same drug coronary radiography has not allergic reaction. Conclusion： It was feasible to forecast the clinical allergic reaction using the non - ionic constrast mediums before coronary angiography. This way has high sensitivity and speciality and no false positive occurs.

关 键 词：冠状动脉造影 造影剂 过敏试验 冠状动脉造影剂 临床应用研究 非离子型造影剂 复方泛影葡胺 碘过敏试验 过敏反应 非离子造影剂 造影术前 回顾性分析 

分 类 号：R540.41[医药卫生—心血管疾病] R780.2[医药卫生—内科学]