1996—2001年住院复治肺结核患者结核分枝杆菌耐药性的调查  

The investigation on drug resistance of hospitalized previously retreated tuberculosis patients during 1996-2001 in our hospital

作　　者：任来兴[1] 桂徐蔚[1] 夏祥新[1] 唐神结[1] 吴小珍[1] 张莹蓉[1] 

机构地区：[1]上海市肺科医院,上海200433

出　　处：《中国防痨杂志》2005年第5期310-312,共3页Chinese Journal of Antituberculosis

摘　　要：目的探讨住院复治肺结核患者的耐药情况。方法对1996—2001年培养阳性的1 385例住院肺结核患者中440例复治肺结核患者的耐药情况按年龄分组进行回顾性分析。结果总耐药率以青年组最高。耐2药及以上者比例较耐1药比例高,青年组耐R率明显高于老年组;耐2药中,以耐HR占首位。总的耐多药率为49.5%,青年组高达73.9%。结论复治肺结核患者的高耐药率应引起足够重视,需采取更多措施降低耐药率。Objective To investigate the situation of drug resistance of hospitalized previously treated pulmonary tuberculosis patients. Method To analyze and compare the drug resistance of 440 cases of retreated pulmonary tuberculosis from 1385 baterilogical positive pulmonary tuberculosis cases during 1996 - 2001. Results The total rate of drug resistance in youth group was the highest. The proportion of 2 and above drugs resistance was higher than that of 1 drugresistance. The rate of R resistance in youth group was obviously higher than that in old age group. The rate of HR resistance was the highest in 2 drug resistance group. The total rate of multi - drug resistance was 49.5% ,but that in youth group was as high as 73.9%. Conclusion We should pay more attention to the grave situation of drug resistance of the patients with retreated pulmonasy tuberculosis. It is important to take the more measures to reduce the rate of drug resistance.

关 键 词：结核 肺 分枝杆菌 结核 抗药性 肺结核患者 结核分枝杆菌 复治 住院 耐药性 耐药情况 回顾性分析 耐药率 年龄分组 

分 类 号：R521[医药卫生—内科学] R378.911[医药卫生—临床医学]