无创正压通气治疗慢性阻塞性肺疾病高碳酸血症的疗效观察  

Clinical study of noninvasive ventilation in COPD patients with hypercapnia

作　　者：刘领[1] 郭忠竹[1] 徐建军[1] 卢青[1] 孙春荣[1] 陶静[1] 吴文杰[1] 李秀业[1] 

机构地区：[1]北京市垂杨柳医院呼吸科,100022

出　　处：《临床内科杂志》2005年第10期672-673,共2页Journal of Clinical Internal Medicine

摘　　要：目的探讨无创正压通气治疗慢性阻塞性肺疾病(COPD)高碳酸血症的价值。方法58例COPD二氧化碳潴留患者随机分入治疗组及对照组,对照组仅行常规药物治疗,治疗组在常规药物治疗的基础上加用无创正压通气治疗。比较治疗开始2小时、24小时、7天两组同期血气、血压、心率、呼吸频率等改善情况。结果治疗组同期血气、血压、心率、呼吸频率等较对照组明显改善(P均<0.05)。结论应用无创通气可明显改善COPD患者症状,提高PO2降低PCO2,对COPD高碳酸血症患者有确切疗效。Objective To evaluate the clinical value of noninvasive ventilation for COPD with hypereapnia. Methods 58 patients with COPD were randomly divided into control and trial group,which received conventional medical therapy and conventional medical therapy plus noninvasive ventilation respectively. The blood gas analysis index,blood pressure,heart rate, breath rate etc were compared between two groups at 2h,24h, in 7 days after treatment. Results Compared with the result of control group,the blood gas analysis index, blood pressure, heart rate, breath rate etc improved significantly in trial group （ P 〈 0.05）. Conclusion Noninvasive ventilation can improve the symptoms and arterial blood gases and is beneficial to COPD with hypereapnia.

关 键 词：无创正压通气 慢性阻塞性肺疾病 高碳酸血症 

分 类 号：R563.9[医药卫生—呼吸系统]