甲状腺激素自身抗体检测的意义  

Significance of Determination of Serum Thyroid Hormone Autoantibodies (THAAb)

作　　者：刘平安[1] 翟春桃[1] 袁素芬[1] 

机构地区：[1]上海第二医科大学附属第九人民医院核医学科,200011

出　　处：《放射免疫学杂志》2005年第5期329-330,共2页Journal of Radioimmanology

摘　　要：目的:检测不同人群血清中的甲状腺激素自身抗体(THAAb)探讨其临床价值。方法:检测甲状腺功能正常的血清107例、甲亢血清56例、甲减血清34例,分别检测其THAAb和甲状腺抗体。结果:甲状腺功能正常组阳性率2.80%,甲亢组阳性率5.35%,甲减组阳性率5.88%。结论:THAAb阳性可影响临床检测的一致性,对临床检测有重要意义。Objective To investigate the clinical value of determination of the prevalence of serum thyroid hormone autoantibodies （THAAb） in populations with different thyroid function status. Methods Serum THAAb,TGA,TMA levels were determined with RIA in 107 euthyroid,56 hyperthyroid and 34 hypothyroid subjects. Results Positiveness of THAAb in euthyroid, hyperthyroid and hypothyroid subjects was 2.80%, 5.35% and 5.88% respectively. Conclusion THAAb was positive in quite a few subjects with various thyroid function status. As the presence of THAAb might interfere with the accuracy of thyroid hormones assays, in doubtful cases the serum samples should be treated with PEG precipitation to remove these antibodies.

关 键 词：甲状腺激素自身抗体 放射免疫分析 甲状腺激素自身抗体 自身抗体检测 甲状腺功能正常 临床检测 甲状腺抗体 临床价值 不同人群 血清 正常组 

分 类 号：R446.62[医药卫生—诊断学] R587.1[医药卫生—临床医学]