福建省1996—2004年围产儿总唇裂畸形监测及研究  

The Prevalence Surveillance of Perinatal Cleft Lip with or without Cleft Palate in Fujian(1996-2004)

作　　者：游昭华[1] 赵秀艳[1] 翁云钦[1] 郑巧玲[1] 

机构地区：[1]福建省妇幼保健院,福州350001

出　　处：《海峡预防医学杂志》2005年第5期15-17,共3页Strait Journal of Preventive Medicine

摘　　要：[目的]描述1996—2004年间福建省围生儿唇裂畸形的流行病学特征。[方法]调查22所县级以上监测医院分娩的孕28周至产后7 d的围生儿。[结果]围生儿总唇裂发生率为12.61/万。其中唇裂4.86/万,唇裂合并腭裂7.75/万;城镇发生率11.44/万,乡村14.21/万;男性14.26/万,女性10.40/万。产妇年龄组间总唇裂发生率类似,年度发生率下降不显著。总唇裂畸形中以单发多见(80.6%),围生期病死率29.7%,其中单发畸形20.0%,多发70.1%。[结论]我省总唇裂发生率下降趋势不显著,仍是我省发生率第一位的先天畸形,男性发生占优势。[Objective] To describe the epidemiological features of perinatal cleft lip with or without cleft palate （CL± P） from 1996 to 2004 in Fujian. [Methods] All live or still births with 28 weeks of gestation to 7 days after birth were assessed in 22 surveillance hospitals. [Results]The prevalence rate of CL±P was 12.61/10 000 （CL and CLP were 4.86/10 000 and 7.75/10 000 respectively）, The rates were 11.44/10 000 and 14.21/10 000 in urban and rural area, and 14.26/ 10 000 and 10.40/10 000 in male and female respectively. There was no significant difference among maternal-age-specific prevalence rates,And no decreasing trend was found during this period. The rate of isolated form in CL±P was 80.6%The perinatal fatality rate of CL± P was 29.7%, and the rate in isolated forms was 20.0%, and in syndromic was 70.1%. [Conclusion] No decreasing trend of prevalence rate of CL± P was observed during 1996-2004. It is still the highest prevalence of birth defect in Fuiian and males were predominant in this defect.

关 键 词：唇裂 唇腭裂 总唇裂 出生缺陷监测 

分 类 号：R726.2[医药卫生—儿科]