S－烷基－O－多氯苯基硫代磷（膦）酸衍生物的合成及杀菌活性研究  

Studies on the Synthesis of S-Alkyl-O-polychlorophenyl Thiophosphoric(─nic) Acid Derivatives and Their Fungicidal Activities

作　　者：唐除痴[1] 金桂玉[1] 黄光燕 马缚鹏[1] 吴桂萍[1] 贺峥杰[1] 李树正[1] 李秉武 张淑华[1] 

机构地区：[1]南开大学元素有机化学研究所

出　　处：《高等学校化学学报》1996年第3期414-418,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金

摘　　要：Ｏ，Ｏ－二烷基硫代磷（膦）酸酯与三氯氧磷发生异构化氯化反应生成Ｓ－烷基硫代磷（膦）酰氯，后者在缚酸剂存在下与多氯酚反应得到标题化合物．此类化合物也可以用传统方法，从Ｓ－烷基硫代磷酰二氯先后与多氯酚及其它亲核试剂反应得到．对所合成的２８个新化合物的平碟试验表明，在０．００５％浓度下对小麦赤霉等１２种植物病菌均表现了明显的抑制活性．The isomerization/chlorination of O,O-dialkyl thiophosphate(-onate)1 with phosphorus oxychloride gives S-alkyl thiophosphorochloride(-nochloride)2,then,the reaction of compounds 2 with polychlorophenol in the presence of triethylamine afford the title compounds 4.Compounds 4 have also been prepared by using the traditional method, thus,the reaction of S-alkyl thiophosphorodichloride 5 with polychorophenol, then with another nucleophile R' H in the presence of triethylamine can also give the title compounds(4).The results of the tests in the fungicidal activity towards the twelve plant disease fungus show that the twenty-eight compounds 4 prepared possess a satisfactory or excellent fungicidal activity.

关 键 词：硫代磷酸醌 有机磷化合物 杀菌活性 

分 类 号：TQ455.43[化学工程—农药化工]