序贯法治疗绝经后骨质疏松症的对比性研究  

Contrast study of treated postmenopausal osteoporosis by ordinal therapy

作　　者：李卫东[1] 吴萍[1] 颜瑞巧[2] 李光辉[3] 王亦东[1] 

机构地区：[1]九江学院医学院医学科研中心,江西九江332000 [2]九江学院附属医院,江西九江332000 [3]华中科技大学同济医学院附属同济医院骨科,湖北武汉430030

出　　处：《中国现代医学杂志》2005年第20期3145-3148,共4页China Journal of Modern Medicine

摘　　要：目的探讨不同的序贯疗法治疗绝经后骨质疏松的效果。方法80例病人随机分成两组:ADFR方法组和DFR方法组;每6个月测量腰椎和股骨近端骨密度(BMD)、胸腰段X光片及实验室检查,结果作对比分析处理。结果两种方法均能使腰椎和股骨近端(股骨颈除外)的BMD增加,但并不能降低骨折发生率,两种方法的效果没有显著差异。结论ADFR疗法的A期用药并不能增加疗效,DFR疗法更适合晚期的骨质疏松患者、费用低、风险相对小。[Objective] To study the effect of dissimilar ordinal therapy on postmenopausal osteoporosis, [Methods] Eighty cases were randomly divided into two groups： ADFR group and DFR group. Each case was measured bone mineral density （BMD） of lumbar and proximal femur, and received the examination of the lumbar X-ray and laboratory every six months, Results were managed with analysis by contrast, [Results] An increase of the BMD was observed in both groups in the lumbar vertebrates and proximal femur （except femoral neck）, [Conclusion] Drug of A scheduled time of ADFR therapy no able to increase curative effect, The DFR therapy even more adapt to afternoon sufferer of osteoporosis, fare is lowliness and hazard is relatively small.

关 键 词：序贯疗法 绝经后骨质疏松 ADFR疗法 DFR疗法 对比性研究 

分 类 号：R589.5[医药卫生—内分泌]