左氧氟沙星治疗COPD合并肺部感染的疗效观察  

Chinical study of levofloxacin in the treatment of respiratory tract bacterial infections with COPD

作　　者：翟洪玉[1] 孙路路[1] 陆非平[1] 

机构地区：[1]北京世纪坛医院,100038

出　　处：《中国现代医药杂志》2005年第5期23-25,共3页Modern Medicine Journal of China

摘　　要：目的观察左氧氟沙星注射液治疗慢性阻塞性肺病(COPD)合并肺部感染的临床疗效及安全性.方法按照患者入院顺序分为2组:A组(33例)选用左氧氟沙星注射液0.2g,静脉点滴,每日2次,7～10天一疗程;B组(32例)选用头孢哌酮钠舒巴坦钠注射液3.0g,静脉点滴,每日2次,7～10天一疗程.结果A组、B组的临床总有效率分别为87.9%、90.6%,细菌清除率为81.8%、88.5%.结论静脉注射左氧氟沙星治疗COPD合并肺部感染高效安全.Objective To evaluate the clinical efficacy and safety of levofloxaein in the treatment of respiratory tract bacterial infections with COPD. Methods Patients with lower respiratory tract infections with COPD were treated with levofloxaein or eefoperazone in a randomized controlled study. Results A total of 65 patients were enrolled in this study, 33 eases were in A group, 32 eases in B group. The cure rates and the effective rates of A and B groups were 87.9%, 90.6% （P〉0.05）, respectively, the bacterial eradication rates of the two groups were 81.8%, 88.5%,respectively. There was no statistical significance between the two groups. Conclusions Levofloxaein is an effective and safety for the treatment of lower respiratory tract bacterial infections with COPD.

关 键 词：左氧氟沙星 细菌感染 慢性阻塞性肺疾病 下呼吸道感染 慢性阻塞性肺病(COPD) 左氧氟沙星注射液 并肺部感染 疗效观察 治疗 舒巴坦钠注射液 临床总有效率 静脉点滴 头孢哌酮钠 

分 类 号：R563.9[医药卫生—呼吸系统]