南风Ⅰ号外用防治长春瑞宾所致静脉炎的临床研究  

Clinical Research of Nanfeng-Ⅰ for External Use in Prevention and Cure of Phlebitis Caused by Vinorelbine

作　　者：张兰凤[1] 王静[1] 谭清和[1] 陆勤美[1] 张慎芳[1] 周平 邵火芳[1] 

机构地区：[1]江苏省南通市肿瘤医院护理部,江苏南通226361 [2]江苏省南通市瑞慈医院护理部,江苏南通226010

出　　处：《解放军护理杂志》2005年第10期12-14,共3页Nursing Journal of Chinese People's Liberation Army

基　　金：南通市卫生局立项课题(03-W0303)

摘　　要：目的观察新型中药复方制剂———南风Ⅰ号防治长春瑞宾所致静脉炎的临床疗效。方法选择以长春瑞宾为主的联合化疗方案第1、8天给药的患者,将自身2次化疗同一注射部位分成预防组和对照组,对预防组患者给予中药南风Ⅰ号涂剂;将已发生静脉炎的患者随机分成治疗组和对照组,治疗组给予南风Ⅰ号外敷治疗,对照组给予硫酸镁外敷对照进行临床观察。结果采用STATA 8.0软件进行统计分析,卡方检验比较预防组和对照组之间以及治疗组和对照之间的差异,均具有显著的统计学意义(P<0.01)。结论新型中药复方制剂———南风Ⅰ号对防治长春瑞宾所致静脉炎具有一定的疗效。Objective To observe the clinical pharmacodynamic action of neotype Chinese herb-compounds, Nanfeng - Ⅰ, in prevention and cure of phlebitis caused by Vinorelbine. Methods Patients underwent combined chemotherapy（ Vinorelbine ＋ Cisplatin） were selected at the first and the eighth day of the therapy. The prevention group （treated with Nanfeng-Ⅰ） and prevention control group were randomly assigned according to 2 chemotherapy points of same vided into treatment group （treated with Nanfeng-Ⅰ） patient. The patients with phlebitis were randomly diand treatment control group （treated with magnesium sulfate）. Results Software STATA 8.0 was applied for statistical analysis. Chi-square criterion was employed to contrast the difference between treatment group and treatment control group as well as the difference between prevention group and prevention control group. Both the 2 differences had statistical significance （ P 〈 0.01 ）. Conclusion Nanfeng-Ⅰ, a neotype Chinese herb-compounds, has some effects in prevention and cure of phlebitis caused by Vinorelbine.

关 键 词：长春瑞宾 静脉炎 中药 

分 类 号：R543.6[医药卫生—心血管疾病]