Convenient and Highly Efficient Inversion of 1β-OH Configuration of trans-Vitamin D_(3)  

作　　者：Yong Bin HAN Jin Ping CHEN Ying Ying LI Bai Ning LIU Guo Qiang YANG Yi LI 

机构地区：[1]Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 [2]Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080 [3]Graduate School, Chinese Academy of Sciences, Beijing 100039

出　　处：《Chinese Chemical Letters》2005年第11期1437-1440,共4页中国化学快报（英文版）

基　　金：to the Major State Basic Research Development Program,Grant No.F2000078100;the National Natural Science Foundation of China(No.20172059)and Chinese Academy of Sciences.

摘　　要：A convenient and highly efficient conversion of 1β-OH-trans-vitamin D3, a main byproduct in synthesis of active vitamin D3, to 1α-OH-trans-vitamin D3 is reported. The conversion could be accomplished in 1 minute with 90% yield.

关 键 词：Vitamin D3 Mitsunobu reaction. 

分 类 号：O629.4[理学—有机化学]