Studies on the Synthesis of Morphinan Alkaloid:Preparation of the Key Allylic Silyl Ether Precursor  

作　　者：Zhen Lei SONG Yong Qiang TU Shuan Hu GAO Yi Jun JIANG Shu Yu ZHANG 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry ＆ Department of Chemistry, Lanzhou University, Lanzhou 730000

出　　处：《Chinese Chemical Letters》2005年第11期1445-1447,共3页中国化学快报（英文版）

基　　金：the financial support of the NNSFC(No.30271488,20021001,and 203900501).

摘　　要：A convergent strategy to the key allylic silyl ether precursor 4 in our synthetic efforts toward morphinan alkaloid is presented. The vital step is the selective 1,2-addition of the organocerium agent of 6 to ketene 5.

关 键 词：Morphinan alkaloid Weinreb amide cerium chloride synthesis. 

分 类 号：O629.3[理学—有机化学]