415例次血液病患者医院感染的临床分析  

ANALYSIS OF THE CLINICAL CHARACTERS AND PREVENTIVE MEASURES OF NOSOCOMIAL INFECTIONS IN 415 ATIENTS WITH HEMATOLOGICAL DISEASE

作　　者：李佩文[1] 罗劲华[1] 赵淑敏[1] 杜玲[1] 

机构地区：[1]广州市东山区人民医院,广东广州510080

出　　处：《现代医院》2005年第11期40-42,共3页Modern Hospitals

摘　　要：目的分析血液病患者医院感染与外周血中性粒细胞数的关系及其感染病原学特点,提出预防感染的相关措施.方法对1999～2005年的415例次血液病住院患者进行回顾性调查分析.结果 415例次血液病患者,204例次发生医院感染,49.16%,中性粒细胞数＜0.5×109/L组感染率91.82%以上,中性粒细胞数≥1.0×109/L组感染率16.30% 以下,组间比较P＜0.05;医院感染发生的主要部位为呼吸道;感染病原菌主要是铜绿假单胞菌、金黄色葡萄球菌、其次是真菌.结论中性粒细胞缺乏是血液病患者医院感染的主要危险因素,呼吸系统是主要的医院感染监控部位,必须加强护理,根据病原菌药物敏感实验选择合理抗生素,以避免感染死亡率增高.Objective To study the clinical characters of real infection in patients with hematological disease, and to find out preventive measures for lowering the infection rate of the patients. Methods The data were analyzed in415 patients with hematological disease inthe hospital. Results 204 patients had nosecomialinfection, 49.16%; The infection rate is up to 91.82% in the patients whose nentrecyte was below 0.5 × 10^9/L, the infection rate is under 16.30% in the patients whose neutrocyte was above 1.0× 10^9/L, （ P 〈0.05）. Respiratory tract infection was the highest; Gram negative bacteria were the most common cause of nosocomial infection. Pseudomonas aeruginosa was account for the most of gram bacterial infection. Conclusion The neutropenia was main risk factor of nosocomial infection in the patients with hematological disease, positive measures should be taken to prevent from nosecomial infection of hematological patients.

关 键 词：血液病 医院感染 中性粒细胞 病原菌 预防 医院感染监控 血液病患者 临床分析 中性粒细胞数 回顾性调查分析 金黄色葡萄球菌 中性粒细胞缺乏 铜绿假单胞菌 药物敏感实验 

分 类 号：R473.78[医药卫生—护理学] R552[医药卫生—临床医学]