大鼠前庭神经内侧核神经元的放电特性及分类  

The discharge characteristics and classifications of rat MVN neuron

作　　者：汪绪武[1] 孔维佳[2] 

机构地区：[1]解放军第456医院耳鼻咽喉科,山东济南250031 [2]华中科技大学同济医学院附属协和医院耳鼻咽喉科,湖北武汉430022

出　　处：《中国耳鼻咽喉颅底外科杂志》2005年第5期297-299,共3页Chinese Journal of Otorhinolaryngology-skull Base Surgery

基　　金：国家杰出青年基金(No.39925035);国家自然科学基金资助(No.30070809);教育部高等学校骨干教师资助计划资助项目

摘　　要：目的探讨大鼠中耳腔冷热水刺激对前庭神经核神经元放电的影响。方法通过向中耳腔灌注冰水(4℃)、热水(44℃)及温水(37℃),以细胞外记录的方式记录前庭神经内侧核神经元放电频率的改变。结果冷热水刺激可引起该前庭神经元的不同变化,其中热水刺激兴奋、冷水刺激抑制的神经元类型最多(A型),刺激停止后神经元放电很快恢复。结论冷热水刺激可引起前庭神经元放电频率的改变,不同神经元的反应各不相同。Objective To detect the effect of caloric stimulation on neuronal discharge in medial vestibular nuclei （MVN）. Methods The middle ear of rats was irrigated by ice （4℃）, hot （44℃） and warm （37℃） water, and the discharge rate of MVN neuron was extracellularly recorded. Results The discharge rate of MVN neuron was changed by caloric stimulation, the majority of MVN neurons showed excitation by hot water and inhibition by ice （type A）. The neuronal discharge recovered immediately after cessation of stimulation. Conclusion MVN neuronal discharge rate is affected by caloric stimulation in middle ear, with different responses in different neurons.

关 键 词：前庭神经核 冷热水刺激 电生理 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]