1-苯基-cis-1,2-环己二醇的合成与表征  

Synthesis and Characteristic of 1-Phenyl-cis-1,2-cyclohexanediol

作　　者：张颂培[1] 陈娟[1] 王文君[2] 郝强[2] 

机构地区：[1]北京工商大学化工学院,北京100037 [2]北京师范大学化学系,北京100087

出　　处：《精细与专用化学品》2005年第22期15-16,19,共3页Fine and Specialty Chemicals

摘　　要：以1-苯基溴化镁和环己酮为原料,利用格氏试剂催化反应得到1-苯基环己醇,之后醇脱水制备α-位取代的环己烯,最后将1-苯基环己烯用过氧化氢氧化、水解制得1-苯基-cis-1,2-环己二醇.通过元素分析、红外光谱与核磁共振谱等手段验证合成产品为目标产物.所得产品的熔点为94～95℃,反应总收率为34.4%.Starting from phenyl magnesium bromide, namely Grignard reagent, and cyclohexanone, 1-phenyl cyclo- hexanol is prepared catalytically, then it is dehydrated to give a-substituted cyclohexene. Finally, 1-phenyl-c/s-1,2-cyclo- hexane-diol can be obtained by the oxidization of 1-arylclohexene with hydrogen peroxide and hydrolysis reaction. The objective compound is confirmed by means of elementary analysis, IR and HNMR. The melting point of the final product is 94-95℃, and the total yield is up to 34. 4%.

关 键 词：环己酮 1-苯基-cis-1 2-环己二醇 格氏试剂 过氧化氢 苯基溴化镁 合成与表征 环己二醇 过氧化氢氧化 催化反应 核磁共振谱 元素分析 红外光谱 

分 类 号：O625.5[理学—有机化学]